Looking for: - Can you take benadryl and prednisone together Click here - Can you take benadryl and prednisone together As a general rule of thumb, pets should never take NSAIDs and corticosteroids at the same time. If it is necessary for a pet who is on one. Syncope (fainting) may occur in association with administration of Pfizer-BioNTech COVID Vaccine has not been approved or licensed by the U. The companies. There is no interaction between prednisone and Benadryl. Summary. Both Benadryl and hydrocodone are considered CNS (central nervous system). ❿ Can you take benadryl and prednisone together. Can You Take Benadryl With Prednisone? I'm taking amoxicillin mg twice a day. There is a general precaution that you should be aware of concerning the administration of corticosteroids like prednisone and thyroid replacement medications like Synthroid. However, the safest option is simply to abstain from alcohol while taking Benadryl. While there certainly is variabi