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Salicylic acid vs. benzoyl peroxide: Benefits and side effects - On this page

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Is Epiduo better than Benzoyl Peroxide? | MDacne.Iodine is not available outside of the United States



  It reduces comedone formation and inflammation. Smooth it onto the affected area. You may find that using it less often, such as once every other day, is enough to control acne.  


Benzoyl peroxide: medicine used to treat acne - NHS



 

Salicylic acid is an acid that is also present in the medication aspirin. Benzoyl peroxide is a chemical present in some bleaching products. People can buy acne products that contain salicylic acid without a prescription. Salicylic acid is in many wash-off and leave-on products in concentrations between 0.

People usually tolerate salicylic acid well, but unfortunately, it has limited efficacy for treating acne. People can also purchase acne medications that contain benzoyl peroxide over the counter. The concentration of benzoyl peroxide in these products ranges from 2. Some acne medications contain benzoyl peroxide in combination with other ingredients. These products are available only by prescription.

Epiduo and Epiduo Forte are two products that contain benzoyl peroxide and a topical retinoid. Salicylic acid helps naturally exfoliate the skin by allowing the skin cells to unstick from one another. This process can stop the formation of pimples. One study compared using 0. People using the salicylic acid product had a more significant reduction in acne compared to those using a placebo.

Some studies have suggested that salicylic acid chemical peels may help improve mild acne. However, people need to use them multiple times, and the results do not last long. Doctors recommend using products that contain salicylic acid one to three times daily. Evidence shows that benzoyl peroxide is effective in improving acne. Doctors recommend using benzoyl peroxide on its own for treating mild acne or with other topical and oral acne medications for more severe conditions.

The widespread use of topical and oral antibiotics to treat acne has led to increasing resistance of the Propionibacterium acnes bacteria that is responsible for causing acne. Doctors may recommend benzoyl peroxide because it helps prevent bacterial resistance. People using benzoyl peroxide products may notice an improvement by the third week of treatment, but they may only see a maximal effect after 2 to 3 months.

Gently pat your skin dry. Put a thin layer of gel on all the affected areas. If your whole face has acne, use a strip of gel 2. Place a small amount of the product onto your hands. Smooth it onto the affected area. Keep the wash on your skin for no more than 1 to 2 minutes. Rinse your face thoroughly with water. You'll usually use the wash 1 or 2 times a day. How long will I use it for?

It depends on how quickly your condition improves. What if I forget to use it? It does not matter if you forget to use benzoyl peroxide. What if I use too much? Important: Important Keep benzoyl peroxide away from your eyes.

Common side effects These common side effects happen in more than 1 in 10 people. Talk to a doctor or pharmacist if these side effects bother you or do not go away: dry skin red or peeling skin burning or stinging skin irritation Serious side effects These serious side effects are rare and happen in less than 1 in 1, people. Stop using benzoyl peroxide if: the skin that you're treating becomes swollen you get blisters on your skin If your symptoms do not get better within a couple of days or if they get worse at any time, contact a doctor straight away.

Serious allergic reaction In rare cases, it's possible to have a serious allergic reaction anaphylaxis to benzoyl peroxide. What to do about: dry skin — apply a moisturiser and lip balm regularly the best type of moisturiser is an oil-free face moisturiser for sensitive skin. Try to take shorter showers, using warm water rather than hot. Do not use other products on your skin in the meantime. Speak to a doctor if your symptoms do not get better or are severe. It might help to stop using the gel for a few days until the irritation goes away, then start again.

If the irritation does not go away after this time, stop using it and speak to a doctor. Benzoyl peroxide and breastfeeding Although it's generally OK to use benzoyl peroxide when you're breastfeeding, do not use it on your chest area and wash your hands before touching your baby. Important: Important Tell a pharmacist or doctor if you're trying to get pregnant, already pregnant or breastfeeding. Mixing benzoyl peroxide with herbal remedies and supplements There's very little information about taking herbal remedies and supplements while using benzoyl peroxide.

Important: Important Tell your doctor or pharmacist if you are taking any other medicines, including herbal remedies, vitamins or supplements. How does it work? Benzoyl peroxide attacks the bacteria on your skin. It works best when you use it regularly. How long does it take to work?

Benzoyl peroxide usually takes about 4 weeks to start working. What can I do if benzoyl peroxide does not work? Is it safe to take for a long time? Are there other acne treatments I can buy? These have different active ingredients including: Azelaic acid cream — attacks the bacteria on your skin. Dry skin, burning sensation and contact dermatitis are common Simple dosing strategies may help to reduce skin irritation.

Evidence snapshot What is known about this drug In a randomised controlled trial, adapalene—BPO with oral doxycycline reduced acne severity rating in more patients than doxycycline alone PBS listing Restricted benefit For acute and maintenance treatment of severe acne vulgaris. May be prescribed by nurse practitioners continuing therapy only Authorised nurse practitioners may prescribe continuing therapy of this medicine after it has been initiated by a medical practitioner.

What is it? Who is it for? Where does it fit? How does it compare? Table 1. Safety issues The common adverse effects of adapalene—BPO — dry skin, burning sensation and contact dermatitis — are characteristic of topical acne therapies; sunburn and pruritus were uncommon.

Antibiotic-related nausea, vomiting and diarrhoea may occur during acute treatment In the week trial comparing adapalene—BPO and doxycycline with doxycycline alone, 9. Reason for PBS listing The Pharmaceutical Benefits Advisory Committee recommended a restricted benefit listing for adapalene—BPO for acute in combination with an oral antibiotic and maintenance treatment of severe acne on the basis of acceptable cost-effectiveness compared with placebo.

Information for patients Provide patients and carers with the following information. Apply a thin film of gel over the entire acne-affected area at night. This will help to prevent acne formation, as well as treat existing acne. Adapalene—BPO can make skin more prone to sunburn. The full benefit of treatment may not be apparent for several months, so patience is required. The antibiotic used during acute treatment may cause gastrointestinal symptoms. It may also increase the risk of photosensitivity.

Benzoyl peroxide can bleach or discolour hair, clothes and bed linen. Do not wash affected skin more than twice a day and use a low-irritant, pH-balanced, soap-free cleanser. Picking or squeezing lesions can make acne worse and increase the risk of permanent scarring. Avoid vigorous scrubbing of affected skin, and using astringent or exfoliating agents. Counsel patients about the condition and its course Acne may have a significant social and emotional impact upon the individual.

Counsel patients that: 15,17 acne is very common among young people, but it will improve with time it is not caused by poor hygiene, and excessive washing can make acne worse no direct link has been found between diet and acne acne is not infectious UV light has little benefit in acne.

The main cause of the extreme irritation many Epiduo users complain about is the Adapalene. Similar adverse effects are seen when Adapalene is used alone in the over the counter Differin gel. Some users of Epiduo complain that the Epiduo caused a flare in their acne in the first weeks of use.

This effect, similar to Accutane induced acne flare-ups, is not desirable and may increase the risk of scars at are the end of the treatment. Dryness and irritation are not a good thing in acne treatment and should be avoided. Once the skin is over irritated by products like Epiduo or Differin the skin barrier of the skin is damaged, causing more inflammation that slows down skin healing and increases the risk for acne breakouts.

   

 

A comparative study of benzoyl peroxide and clindamycin phosphate for treating acne vulgaris - Latest news



   

Speak to a doctor if your skin does not improve with benzoyl peroxide, or if acne is making you feel very unhappy.

They may recommend antibiotics or stronger creams. These treatments are only available on prescription. It is generally OK to use Benzoyl peroxide for a long time, as long as you do not have any serious side effects. When you stop using benzoyl peroxide you may find that acne comes back. You may want to keep using it to keep acne under control. You may find that using it less often, such as once every other day, is enough to control acne. Benzoyl peroxide is usually one of the first treatments recommended for mild to moderate acne.

However, there are other types of acne creams, lotions and gels available to buy from a pharmacy. These have different active ingredients including:. Azelaic acid cream — attacks the bacteria on your skin. It also reduces the growth of hard skin cells which block your pores and can cause spots. Glycolic acid or lactic acid — helps remove dead skin cells and reduce inflammation. It improves the appearance of acne scars and makes pores look smaller.

Sulphur or sulfur — removes dead skin cells that cog pores and helps remove excess oil. It is usually combined with other active ingredients. There is no evidence that eating chocolate or greasy foods causes spots.

However, eating a healthy, balanced diet is recommended because it's good for your heart and your health in general. No, it will not affect any type of contraception, including the combined pill and emergency contraception.

There's no clear evidence that using benzoyl peroxide will affect male or female fertility. Page last reviewed: 6 September Next review due: 6 September Benzoyl peroxide On this page About benzoyl peroxide Key facts Who can and cannot use benzoyl peroxide How and when to use it Side effects How to cope with side effects Pregnancy and breastfeeding Cautions with other medicines Common questions. About benzoyl peroxide Benzoyl peroxide is used to treat acne.

You'll usually use it 1 or 2 times a day. The most common side effect is skin irritation. It is better to use it less often at first, then build up as your skin gets used to it. Benzoyl peroxide is also an ingredient in Duac Once Daily with clindamycin, an antibiotic and Epiduo gel with adapalene, a retinoid. Most adults and children over 12 years old can use benzoyl peroxide. Benzoyl peroxide is not suitable for some people. To make sure benzoyl peroxide is safe for you, tell your doctor before using this medicine if you: are allergic to benzoyl peroxide or other medicines.

These need to be treated by a doctor to avoid scarring. Benzoyl peroxide is for use on your skin only. Always wash your hands before and after using this medicine. Gently pat your skin dry. Put a thin layer of gel on all the affected areas. If your whole face has acne, use a strip of gel 2. Place a small amount of the product onto your hands. Smooth it onto the affected area. Keep the wash on your skin for no more than 1 to 2 minutes. Rinse your face thoroughly with water. You'll usually use the wash 1 or 2 times a day.

How long will I use it for? It depends on how quickly your condition improves. What if I forget to use it? It does not matter if you forget to use benzoyl peroxide. What if I use too much? Important: Important Keep benzoyl peroxide away from your eyes.

Common side effects These common side effects happen in more than 1 in 10 people. Talk to a doctor or pharmacist if these side effects bother you or do not go away: dry skin red or peeling skin burning or stinging skin irritation Serious side effects These serious side effects are rare and happen in less than 1 in 1, people.

Stop using benzoyl peroxide if: the skin that you're treating becomes swollen you get blisters on your skin If your symptoms do not get better within a couple of days or if they get worse at any time, contact a doctor straight away.

Serious allergic reaction In rare cases, it's possible to have a serious allergic reaction anaphylaxis to benzoyl peroxide. What to do about: dry skin — apply a moisturiser and lip balm regularly the best type of moisturiser is an oil-free face moisturiser for sensitive skin.

Try to take shorter showers, using warm water rather than hot. Do not use other products on your skin in the meantime. Speak to a doctor if your symptoms do not get better or are severe.

It might help to stop using the gel for a few days until the irritation goes away, then start again. If the irritation does not go away after this time, stop using it and speak to a doctor. Benzoyl peroxide and breastfeeding Although it's generally OK to use benzoyl peroxide when you're breastfeeding, do not use it on your chest area and wash your hands before touching your baby. Important: Important Tell a pharmacist or doctor if you're trying to get pregnant, already pregnant or breastfeeding.

Mixing benzoyl peroxide with herbal remedies and supplements There's very little information about taking herbal remedies and supplements while using benzoyl peroxide.

Important: Important Tell your doctor or pharmacist if you are taking any other medicines, including herbal remedies, vitamins or supplements. How does it work? Benzoyl peroxide attacks the bacteria on your skin. It works best when you use it regularly.

How long does it take to work? Benzoyl peroxide usually takes about 4 weeks to start working. What can I do if benzoyl peroxide does not work?

Is it safe to take for a long time? Are there other acne treatments I can buy? These have different active ingredients including: Azelaic acid cream — attacks the bacteria on your skin. Salicylic acid — helps prevent pores from becoming clogged.

Are there prescription treatments for acne? Prescription-only treatments for acne include: antibiotics creams , gels, solutions or lotions such as clindamycin — attack the bacteria on your skin.

This may help to prevent you getting oily skin which can cause spots. Similar adverse effects are seen when Adapalene is used alone in the over the counter Differin gel.

Some users of Epiduo complain that the Epiduo caused a flare in their acne in the first weeks of use. This effect, similar to Accutane induced acne flare-ups, is not desirable and may increase the risk of scars at are the end of the treatment. Dryness and irritation are not a good thing in acne treatment and should be avoided.

Once the skin is over irritated by products like Epiduo or Differin the skin barrier of the skin is damaged, causing more inflammation that slows down skin healing and increases the risk for acne breakouts. Fortunately, new benzoyl peroxide formulations use a special microparticle benzoyl peroxide and anti-inflammatory ingredients.

These special formulations reduce the irritation that was common with old formulations and further improve the efficacy of this great topical treatment. Is Epiduo more effective than the new micronized benzoyl peroxide anti-acne medications? Regarding efficacy, it seems that the Epiduo has similar efficacy to benzoyl peroxide products but with significantly higher irritation.

As this combination of a highly irritating compound Adapalene with regular BP is not tolerated by most users it may hurt commitment to treatment and reduce treatment success with this product.

In acne, more expensive is not necessarily better. New formulations of the highly effective micronized benzoyl peroxide, are affordable, significantly less irritating and more effective than higher priced prescription topical. To find the right acne treatments for your unique skin, take the free skin assessment by clicking here.



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